My poor 14 yr old dachshund had intermittent diarrhea for about 9 months. His vet put him on 2 courses of metronidazole and wanted to do a 3rd and each course being longer than the last. She changed his food, 3 times. Put him on "other" probiotics, each change came with a minimum of a month of taking the "wait and see" approach. The vet finally did a "diarrhea panel" on him and found out his gut bacteria were completely out of whack. I refused the 3rd course of metronidazole and went in search of something else that might help. In the meantime, my little green machine had become my new best friend. I started putting my dogs in the bathroom whenever I left home, my poor boy was also forced to sleep in a crate rather than on my bed, which he had done most of his life. I felt horrible, but he would have the diarrhea in the middle of the night, on my bed. Nothing worse than that wakeup call! During my research for an answer, I stumbled across doggie biome. I consulted my vet and she checked the products out as well. I had nothing to lose so gave it a shot. I chose the GMP. He is almost done with his first bottle. Although in the first 3 weeks he had a few bouts of diarrhea, which I expected as probiotic/prebiotics take time to be effective..... he has had none since and I am ever grateful!!! I had seriously considered euthanizing him as he was absolutely miserable. When you can hear your dogs gut rumbling from across the room and can see the look of agony on his face, you just want to fix things so badly. However, when you have felt like you've done all you can? I am forever grateful for this product; it literally saved my dogs life! He is back on his normal diet, he is gaining back the weight he had lost, I no longer hear his gut rumblings, and he no longer looks at me with those eyes that say, "momma help me". He is once again my happy little boy! Thank you!